Mosareza Tadayyonfar; Mehdi Amadani; Ali Tajabadi; Yaser Tabaraee; Hossein Khosrojerdi
Volume 23, Issue 1 , May and June 2016, , Pages 14-20
Abstract
Background & Objectives: Pain after surgery, especially in appendectomy, is one of the most common causes of patients’ dissatisfaction. Regarding common side effects of existing analgesics, the researchers decided to replace conventional medicine for overcoming postoperative pain in such patients. ...
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Background & Objectives: Pain after surgery, especially in appendectomy, is one of the most common causes of patients’ dissatisfaction. Regarding common side effects of existing analgesics, the researchers decided to replace conventional medicine for overcoming postoperative pain in such patients. Therefore, the aim of this study is to compare the pain relief effects of diclofenac and promethazine in patients with appendectomy. Materials & Methodes: This triple blind clinical trial was performed on 60 patients of 49 -15 years old undergoing appendectomy in Shahid Doctor Beheshti Hospital of Sabzevar in 2012. Participants were selected by convenience sampling and randomly divided into two 30-cases groups of control and intervention, respectively received diclofenac promethazine by muscle depth injection in Dursuglutyal muscle. According to the standard numeric pain scale, the pain was investigated in the first hours after treatment. Data were analyzed using the Pearson chi-square test and SPSS version 18, and the level of significance was selected as 0.05. Results: The difference of postoperative pain relief was significant (P=0/018) between the two groups at a half an hour. The average amount of pain in half an hour after injection of diclofenac and promethazine were 5.04± 2.26 and 3.96 ± 1.33, respectively. Also, the average amount of pain in one hour after injection of diclofenac and promethazine were 4.59 ± 5/31 and 3.30 ± 1.33, respectively. However, the differences were not statistically significant (P = 0.177). Conclusion: Promethazine is of greater analgesic efficacy than diclofenac. Therefore, a basic planing is recommended for the use of phenothiazines instead of highly morbid analgesics like non -steroidal anti-inflammatory drugs.
Mosareza Tadayyonfar; Hossein Khosrojerdi; Mehdi Amadani; Ali Tajabadi; yaser Tabarraee
Volume 22, Issue 4 , September and October 2015, , Pages 589-595
Abstract
Background: Pain after appendectomy surgery is the most common patients' dissatisfaction which the easiest method of treatment is opioids. Side effects of them led to using more appropriate medications instead of opioids to relieve the pain. Aim of This study was to compare the pain relief effects of ...
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Background: Pain after appendectomy surgery is the most common patients' dissatisfaction which the easiest method of treatment is opioids. Side effects of them led to using more appropriate medications instead of opioids to relieve the pain. Aim of This study was to compare the pain relief effects of morphine and promethazine in patients with appendectomy. Materials and Methods : This triple blind clinical trial was carried out on 60 patients in 49 -15 years old undergoing appendectomy in Shahid Beheshti Hospital in Sabzevar, Iran, 1391.Participants were selected using by convenience method and then randomly divided into two groups of 30 ones. The control and intervention group was injected narcotic and promethazine, respectively. The level of pain was investigated according to the standard numeric pain scale, in the first hour after treatment. Data was analyzed using the Pearson and chi-square test by means of SPSS version 18 in the level of significance of 0.05. Results: there was observed a significant difference between two groups in the level of postoperative pain relief, (P = 0/000), so that the level of pain after injection of promethazine 3/30 ± (1/33) was less than morphine 6/07± (1/23). Also, this difference was significant in half an hour after surgery (p = 0/000) with mean score of 3/69 ± (1/33) and 6/74± (1/30) for Promethazine and morphine, respectively. Conclusion: According to these results, basic planning to use phenothiszines such as promethazine instead of opioids is suggested.